Experimental Evolution of Pathogenesis: “Patient” Research
نویسندگان
چکیده
منابع مشابه
Experimental Evolution of Pathogenesis: “Patient” Research
Twenty-five years and over 50,000 bacterial generations ago, one of the longest open-ended experiments in modern times began when the Lenski laboratory started passaging Escherichia coli under conditions of limited glucose as a carbon source [1]. Later that same year, a paper was published describing a new method for DNA sequencing, called pyrosequencing, that would ultimately light a path towa...
متن کاملMolecular Research on Emerging Viruses: Evolution, Diagnostics, Pathogenesis, and Therapeutics
Viruses are increasingly recognized as emerging infectious disease agents in both humans and animals.[...].
متن کاملPathogenesis of Experimental Cholera
Choleragen, a diarrheagenic protein enterotoxin elaborated by Vibrio cholerae, has been isolated from the supernate of fermenter cultures by steps involving ammonium sulfate precipitation, DEAE cellulose, Sephadex G-75, and Agarose A-5m chromatography. The resulting product appears to be pure according to immunoelectrophoretic, disc electrophoretic, ultracentrifugal, and immunologic criteria. S...
متن کاملPathogenesis of Experimental Shock
Fatal shock was produced in animals by drum trauma, temporary occlusion of the superior mesenteric artery, and bacterial endotoxin. Measurements were made of release of beta glucuronidase and cathepsins from the large granule fractions of livers, and of levels of circulating beta glucuronidase and acid phosphatase in these animals. Experiments were also carried out with animals rendered toleran...
متن کاملThe patient voice in research—evolution of a role
PLAIN ENGLISH SUMMARY Engaging patients in research studies is becoming more common because it makes research and its results more relevant for patients. It is important to understand the best ways for patients and researchers to work together. Patients who are included as active partners in research can provide useful input on what it is like to work on a research team but very little has been...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2013
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1003340